Left Globus Pallidus (Globus pallidus sinister)

Layer: Organs

Educational content only — not medical advice.

Anatomy

The left globus pallidus (paleostriatum) is a subcortical triangular nuclear structure situated medial to the putamen and lateral to the posterior limb of the internal capsule. Divided by the internal medullary lamina into the internal (GPi) and external (GPe) segments, GPi serves as the major inhibitory GABAergic output gateway of the basal ganglia, projecting to the thalamus.

Clinical notes

Deep brain stimulation (DBS) targeting the globus pallidus internus (GPi) is an effective neurosurgical therapy for refractory generalized dystonia and advanced Parkinson disease motor fluctuations.

Related structures

Educational references

FAQ

What is the role of the Left Globus Pallidus?

The left globus pallidus (paleostriatum) is a subcortical triangular nuclear structure situated medial to the putamen and lateral to the posterior limb of the internal capsule. Divided by the internal medullary lamina into the internal (GPi) and external (GPe) segments, GPi serves as the major inhibitory GABAergic output gateway of the basal ganglia, projecting to the thalamus.

Why is the Left Globus Pallidus clinically important?

Deep brain stimulation (DBS) targeting the globus pallidus internus (GPi) is an effective neurosurgical therapy for refractory generalized dystonia and advanced Parkinson disease motor fluctuations.

Source & license

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