Corpus Callosum (Corpus callosum)
Educational content only — not medical advice.
Anatomy
The corpus callosum is the largest commissural white matter tract in the human brain, arching beneath the cerebral cortex in the longitudinal cerebral fissure. Comprising approximately 200 million myelinated axons organized into the rostrum, genu, body (truncus), and splenium, it facilitates bidirectional interhemispheric communication, sensory integration, and coordinated motor planning.
Clinical notes
Surgical corpus callosotomy (split-brain procedure) is performed to prevent interhemispheric propagation of intractable epileptic seizures; complete agenesis of the corpus callosum presents with variable neurodevelopmental delays and impaired social cognition.
Related structures
Educational references
FAQ
What is the role of the Corpus Callosum?
The corpus callosum is the largest commissural white matter tract in the human brain, arching beneath the cerebral cortex in the longitudinal cerebral fissure. Comprising approximately 200 million myelinated axons organized into the rostrum, genu, body (truncus), and splenium, it facilitates bidirectional interhemispheric communication, sensory integration, and coordinated motor planning.
Why is the Corpus Callosum clinically important?
Surgical corpus callosotomy (split-brain procedure) is performed to prevent interhemispheric propagation of intractable epileptic seizures; complete agenesis of the corpus callosum presents with variable neurodevelopmental delays and impaired social cognition.
Source & license
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